| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347153 | Confirmatory screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347167 | Vero cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347152 | Confirmatory screen NINDS AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347163 | 384 well plate NINDS AMC confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347169 | Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347149 | Furin counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347157 | Confirmatory screen GU Rhodamine qHTS for Zika virus inhibitors qHTS | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347161 | Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347164 | 384 well plate NINDS Rhodamine confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347158 | ZIKV-mCherry secondary qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347156 | DAPI mCherry counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347168 | HepG2 cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID599157 | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for ternary enzyme-substrate-inhibitor complex using NAD+ substrate by Lineweaver-Burk plot method | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. |
| AID411277 | Inhibition of human recombinant Gcn5 assessed as reduction in acetylated histone H3 level at 0.2 mM by Western blot analysis in presence of histone H3 | 2009 | Journal of medicinal chemistry, Jan-22, Volume: 52, Issue:2
| A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone. |
| AID331953 | Inhibition of recombinant CBP in human U937 cells at 50 uM | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases. |
| AID499438 | Inhibition of human recombinant histone deacetylase PCAF by ELISA | 2010 | Bioorganic & medicinal chemistry, Aug-15, Volume: 18, Issue:16
| Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. |
| AID599154 | Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli using GAPDH and D-glyceraldehyde-3-phosphate | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. |
| AID348951 | Antibacterial activity against Streptococcus mutans ATCC 25175 after 2 days by twofold broth dilution method in presence of anethole | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Design and evaluation of anacardic acid derivatives as anticavity agents. |
| AID392682 | Inhibition of human GST-fused histone acetyltransferase PCAF in U937 cell nuclear extracts assessed as remaining enzyme activity at 50 uM | 2009 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 19, Issue:4
| Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases. |
| AID639349 | Inhibition of Tip60-mediated histone H3 acetylation in rat brain extracts at 30 uM after 15 mins by ELISA | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID332458 | Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPA preincubated for 5 mins before L-DOPA addition | 1994 | Journal of natural products, Apr, Volume: 57, Issue:4
| Tyrosinase inhibitors from Anacardium occidentale fruits. |
| AID283326 | Inhibition of Saccharomyces cerevisiae recombinant GCN5 assessed as histone H3 acetylation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3
| Quinoline derivative MC1626, a putative GCN5 histone acetyltransferase (HAT) inhibitor, exhibits HAT-independent activity against Toxoplasma gondii. |
| AID321461 | Binding affinity to human AURA expressed in baculovirus in presence of ATP | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID499439 | Inhibition of human recombinant histone deacetylase PCAF at 1 mM by ELISA | 2010 | Bioorganic & medicinal chemistry, Aug-15, Volume: 18, Issue:16
| Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. |
| AID367364 | Inhibition of recombinant p300 | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. |
| AID392678 | Inhibition of human histone acetyltransferase in U937 cell nuclear extracts at 50 uM | 2009 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 19, Issue:4
| Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases. |
| AID599159 | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for ternary enzyme-substrate-inhibitor complex using D-glyceraldehyde-3-phosphate substrate by Lineweaver-Burk plo | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. |
| AID348950 | Antibacterial activity against Streptococcus mutans ATCC 25175 after 2 days by twofold broth dilution method | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Design and evaluation of anacardic acid derivatives as anticavity agents. |
| AID332456 | Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPA | 1994 | Journal of natural products, Apr, Volume: 57, Issue:4
| Tyrosinase inhibitors from Anacardium occidentale fruits. |
| AID332455 | Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPA at 0.8 mM | 1994 | Journal of natural products, Apr, Volume: 57, Issue:4
| Tyrosinase inhibitors from Anacardium occidentale fruits. |
| AID639351 | Inhibition of Tip60-mediated histone H4 acetylation in human HeLa nuclear extracts at 200 uM after 15 mins by ELISA | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID392917 | Inhibition of human immunoprecipitated histone acetyltransferase p300 in U937 cell nuclear extracts assessed as remaining enzyme activity at 50 uM | 2009 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 19, Issue:4
| Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases. |
| AID499441 | Inhibition of histone deacetylase PCAF in human HepG2 cells assessed as decrease in SAHA-induced histone H4 acetylation levels at 60 uM after 24 hrs by Western blotting | 2010 | Bioorganic & medicinal chemistry, Aug-15, Volume: 18, Issue:16
| Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. |
| AID321460 | Binding affinity to human AURA expressed in baculovirus | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID321466 | Activation of human AURB autophosphorylation activity | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID367362 | Inhibition of recombinant Tip60 (1-513) expressed in Escherichia coli BL21 (DE3) by liquid scintillation | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. |
| AID639346 | Inhibition of Tip60-mediated histone H3 acetylation in human HeLa nuclear extracts at 200 uM after 15 mins by ELISA | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID599155 | Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli using GAPDH and D-glyceraldehyde-3-phosphate in presence of 0.01% Triton X-100 | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. |
| AID604032 | Inhibition of human recombinant KAT3A expressed in Escherichia coli BL21 using histone H4 peptide as substrate at 50 uM after 2 hrs relative to control | 2011 | Bioorganic & medicinal chemistry, Jun-15, Volume: 19, Issue:12
| Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs). |
| AID639352 | Inhibition of human MOF expressed in Escherichia coli BL21(DE3) cells using [14C]AC-CoA and histone H4 as substrate after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID367361 | Inhibition of His6x-tagged yeast recombinant Esa1 (105-445) expressed in Escherichia coli BL21 (DE3) by liquid scintillation | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. |
| AID321464 | Activation of human AURA activity expressed in baculovirus cells by time course assay | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID321458 | Activation of human AURA mediated histone H3 phosphorylation by phosphoimager analyzer | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID392681 | Inhibition of human histone acetyltransferase GCN5 in U937 cell nuclear extracts assessed as remaining enzyme activity at 50 uM | 2009 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 19, Issue:4
| Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases. |
| AID321463 | Activity of human AURA expressed in baculovirus at 50 uM by phosphorimager analyzer | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID332457 | Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPA by Lineweaver-Burke plot analysis | 1994 | Journal of natural products, Apr, Volume: 57, Issue:4
| Tyrosinase inhibitors from Anacardium occidentale fruits. |
| AID639338 | Inhibition of human recombinant His-tagged p300 HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate at 200 uM after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID639342 | Inhibition of human recombinant His-tagged PCAF HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate at >200 uM after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID639340 | Inhibition of human recombinant His-tagged PCAF HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID321457 | Activation of human AURB mediated histone H3 phosphorylation by phosphoimager analyzer | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID289702 | Antimicrobial activity against Mycobacterium smegmatis str. MC2 155 after 24 hrs at 100 ug/ml by broth dilution method | 2007 | European journal of medicinal chemistry, Mar, Volume: 42, Issue:3
| Synthesis of isonicotinoylhydrazones from anacardic acid and their in vitro activity against Mycobacterium smegmatis. |
| AID347652 | Inhibition of recombinant His-tagged HAT p300 expressed in Sf21-Baculovirus system | 2009 | Bioorganic & medicinal chemistry, Jan-15, Volume: 17, Issue:2
| Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs). |
| AID639343 | Inhibition of human recombinant His-tagged p300 HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate at >200 uM after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID639336 | Inhibition of His-tagged human recombinant Tip60 expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate at 200 uM after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID639350 | Inhibition of Tip60-mediated histone H4 acetylation in rat brain extracts at 30 uM after 15 mins by ELISA | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID321467 | Ratio of Kcat for human AURA to Km for human AURA | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID639348 | Inhibition of Tip60-mediated histone H4 acetylation in human HeLa nuclear extracts at 50 uM after 15 mins by ELISA | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID367606 | Inhibition of TIP60 in human HeLa cell extracts by ELISA | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. |
| AID599156 | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for binary enzyme-inhibitor complex using NAD+ substrate by Lineweaver-Burk plot method | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. |
| AID639347 | Inhibition of Tip60-mediated histone H3 acetylation in human HeLa nuclear extracts at 50 uM after 15 mins by ELISA | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID613126 | Inhibition of recombinant human p300/CBP using [3H]-acetyl CoA at 50 uM after 2 hrs by scintillation counting relative to control | 2011 | Bioorganic & medicinal chemistry, Jun-15, Volume: 19, Issue:12
| Epigenetic profiling of the antitumor natural product psammaplin A and its analogues. |
| AID272386 | Inhibition of HAT in human U937 cells at 50 uM | 2006 | Journal of medicinal chemistry, Nov-16, Volume: 49, Issue:23
| Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties. |
| AID639341 | Inhibition of human recombinant His-tagged p300 HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID321465 | Activation of human AURA autophosphorylation activity | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID332912 | Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method | 1994 | Journal of natural products, Jan, Volume: 57, Issue:1
| Naturally occurring antiacne agents. |
| AID348953 | Antibacterial activity against Escherichia coli ATCC 9637 up to 200 ug/ml after 2 days by twofold broth dilution method | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Design and evaluation of anacardic acid derivatives as anticavity agents. |
| AID639337 | Inhibition of human recombinant His-tagged PCAF HAT domain expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate at 200 uM after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID499440 | Inhibition of histone deacetylase PCAF in human HepG2 cells assessed as decrease in SAHA-induced histone H4 acetylation levels at 30 uM after 24 hrs by Western blotting | 2010 | Bioorganic & medicinal chemistry, Aug-15, Volume: 18, Issue:16
| Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. |
| AID367365 | Inhibition of PCAF HAT domain (493-658) expressed in Escherichia coli BL21 (DE3) | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. |
| AID599158 | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for binary enzyme-inhibitor complex using D-glyceraldehyde-3-phosphate substrate by Lineweaver-Burk plot method | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. |
| AID639339 | Inhibition of human recombinant His-tagged Tip60 expressed in Escherichia coli BL21(DE3) cells using [14C]Ac-AoA and histone H4 as substrate after 5 mins by scintillation counting | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1
| 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
| AID392680 | Inhibition of human GST-fused histone acetyltransferase CBP in U937 cell nuclear extracts assessed as remaining enzyme activity at 50 uM | 2009 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 19, Issue:4
| Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases. |
| AID411273 | Inhibition of human recombinant Gcn5 assessed as reduction in acetylated histone H3 level at 0.2 mM by Western blot analysis | 2009 | Journal of medicinal chemistry, Jan-22, Volume: 52, Issue:2
| A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone. |
| AID321459 | Activation of human AURA assessed as histone H3 phosphorylation | 2008 | Journal of medicinal chemistry, Feb-28, Volume: 51, Issue:4
| Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. |
| AID1801107 | DPPS Inhibition (trans FPP based) Assay from Article 10.1111/cbdd.12463: \\A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery.\\ | 2015 | Chemical biology & drug design, Jun, Volume: 85, Issue:6
| A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |